Farmasötik ve nutrasötik endüstrilerde, En çok kullanılan dozaj formlarından biri kapsüllerdir. Birçok Kapsül türleri bir dizi amaca hizmet etmek için var, ve buna göre, kapsül türlerinin kütle üretiminin mümkün olmasını sağlayan kapsül doldurma makineleri türleri vardır..

Gibi sorularınız olabilir: Farklı kapsül türleri nelerdir? Farklı kapsül türlerini doldurabilen çok yönlü bir kapsül yapmak? Verimli bir kapsül dolum makinesi nasıl seçilir?

Bu makale öncelikle kapsül dolgularının önemli özelliklerini gösterecektir, aşağıdaki çeşitli kapsül türlerinin listeleriyle, onları yapan kapsülleri ve makineleri daha iyi anlamanıza izin vermek.

Önde gelen çok yönlü kapsül dolum makinelerinin temel özellikleri nelerdir?

İlaç endüstrisinde, otomatik kapsül dolum makineleri are critical for precise and efficient production. High-performance and versatile capsule fillers are designed to meet mass production demands while making sure of flexibility and precision. Key features include:

Çok yönlülük: These machines are capable of handling various types of capsules, including gelatin, vejetaryen, and starch-based capsules. This adaptability ensures manufacturers can produce a wide range of products without multiple machines.

High Production Capacity: Advanced machines can achieve the maximum production output of up to 300,000 saatte kapsül, making them ideal for large-scale manufacturing.

Modüler Tasarım: Modularity simplifies operation and maintenance. Operators can easily switch between different dozaj kapsül sizes and types, reducing downtime and increasing efficiency.

High Precision in Powder Filling: Leading machines offer exceptional accuracy in powder filling with minimal deviation, Tutarlı dozu sağlamak ve israfı azaltmak için.

Otomasyon: Otomatik kapsül besleme gibi otomasyon, doldurma, kilitleme, ve kusurlu kapsüllerin reddedilmesi üretim sürecini kolaylaştırır, Verimliliği artırmak ve işçilik maliyetlerini azaltmak.

Düşük hata oranları: Üst düzey kapsül dolgu doldurma, çok yönlülüğe sahip dolgu makineleri, 0.1%, Yüksek verim kalite kapsül garantisi.

CGMP ŞövalyeCE: Farmasötik işleme için CGMP standartlarına uygun olmak gereklidir. Önde gelen makineler kesinlikle katı standartları karşılayabilir, Ürün kalitesini garanti etmek.

Toz Kontrolü ve Temizlik: Gelişmiş sızdırmazlık mekanizmaları ve toz ekstraksiyon sistemleri kontaminasyonu önler, Temiz bir üretim ortamının korunması.

Büyük ölçekli üretim için doğru kapsül doldurma makinesini nasıl seçilir

Büyük ölçekli üretim ihtiyaçları olan üreticiler için, Doğru kapsül dolgu doldurma makinesini seçmek çok önemlidir. Birkaç temel husus önemli, üretim kapasitesi gibi. Makinenin gerekli çıktınızı karşılayabildiğinden emin olun.

Otomatik kapsül dolgu makinesinin lider üreticisi olarak, Jinlu paketleme işçiliği destekliyor ve güvenilir farmasötik ekipmanlar üretiyor. Kapsülleme alanında, NJP-7800D, Son teknoloji ürünü bir farmasötik kapsül makinesi, Kapsül doldurma teknolojisinin zirvesini örneklendirir.

Bu otomatik kapsül dolum makinesini tanıtarak, Kullanıcılar, en yeni çok yönlü kapsül üreticisi makinesinin çeşitli temel özellikleriyle tanışabilir, Yaygın tuzaklardan kaçınmak ve sorunsuz bir şekilde sağlamak için, Verimli Üretim Deneyimi.

Ekipman çok yönünde, Makine farklı kapsül tiplerini ve tüm kapsül boyutlarını barındırır, Üreticilere benzersiz esneklik sağlamak. Maksimum çıktı ile 468,000 kapsül/saat, Bu otomatik kapsül dolgu maddesi büyük ölçekli üretim için tasarlanmıştır.

Yüksek düzeyde otomasyon ile donatılmış, Tüm üretim sürecini otomatikleştirir, kapsül besleme dahil, ayrılma, doldurma, kilitleme, ve atık reddi, İşgücü maliyetlerini azaltmak. Ek olarak, Gelişmiş pnömatik besleme sistemi, üstün doldurma doğruluğu sağlar. Makine, bir kapsül ayırma başarı oranı elde eder. 99.99% ve ürün yeterlilik oranı 99.8%.

Modülerlik ve kullanıcı dostu tasarım, bu makinenin kapsüller yapmak için standart özellikleridir. CGMP standartlarına tamamen uyumlu, Yerleşik akıllı yağlama sistemi, sızıntı olmadan sürekli yağlama sağlar, Temiz bir üretim ortamının korunması.

Pırıltılı noktalardan biri, NJP kapsül dolum makinesi, en yeni teknolojileri içerir, Hassas indeksleme için bir Alman Zeiss optik indeksleme kafası ve gelişmiş stabilite için CNC-işlenmiş bir dahili kamera dahil. SIL ithal silikon contalarla donatılmış patentli pikaplı tasarım, tozun döner tabloya girmesini etkili bir şekilde önler, tozsuz bir işlemin sağlanması.

Malzemelere göre kapsül türleri

Yukarıda belirtildiği gibi, Çok yönlü bir otomatik kapsül doldurma makinesi doldurabilir Kapsül türleri. Fakat, Kapsüller farklı tiplerde nasıl sınıflandırılır? İşte bu konu hakkında bir fikir.

Sorabilirsin: Medicine kapsüller nelerdir? Jel kapsülü nedir? Malzemeye göre kategorize edildi, Kapsül türleri aşağıda gösterildiği gibi içerik olabilir:

1. Jelatin Kapsüller

Esas olarak hayvanlardan elde edilen jelatinden üretildi (sığır ve balık gibi) Deriler ve Kemikler, Jelatin kapsülleri, ilaçları kapsayan geleneksel bir kapsül formudur, takviyeler veya diğer aktif malzemeler. Örneğin, balık yağını kapsüllemek için, fish gelatin capsules are ideal for their desirable resolvability with aliphatic acid.

Gelatin is biocompatible, biodegradable and non-toxic, and it has benefits including the ease of swallowing, staying tasteless and odorless, and rapid dissolution. Dahası ne var, gelatin capsules have better performance in their long shelf life.

Ek olarak, by controlling the dissolution rate and release degree of active ingredients in the gastrointestinal tract, gelatin capsules enable the drug to be released at specific parts in a human body, playing a role of targeted therapy.

2. Vejetaryen kapsüller

For vegetarian consumers who prefer plant-based diets, vegetarian capsules, inclusive of HPMC capsules and pullulan ones, are a good option. Vegetarian capsules do not contain animal-derived allergens, and ingredients are natural and healthy. Öyleyse, for those allergic to animal proteins, this type of capsules obviously reduces the risk of allergic reactions.

There is an issue of gelatin vs vegetarian capsules. In comparison with gelatin capsules, vegetarian capsules enjoy wider consumer acceptance, enhanced chemical stability and pH compatibility, and friendliness to environmental sustainability. Fakat, in the aspect of cost, vegetarian capsules are 3 times more expensive than gelatin ones.

2-1 HPMC Capsules

HPMC capsules are made from hydroxypropyl methylcellulose, a water-soluble polymer gained from cellulose. Herbal products, such as Comvita immune propolis and PSeti quercetin, are packaged in HPMC capsules due to their effectiveness in ensuring product quality.

What Are HPMC Capsules’ Advantages over Pullulan Capsules?

· With raw materials derived from wood pulp or cotton, HPMC capsules are generally of lower costs compared to pullulan capsules, and the large-scale production is more economical.

· Due to the cost-effectiveness and the well-established supply chain, HPMC capsules are more commonly used than pullulan capsules in pharmaceutical industry.

· Owning the chemical stability across a wide pH range (acidic to alkaline), HPMC are compatible with a broader range of formulations.

2-2 Pullulan Capsules

In terms of pullulan capsules made from fermented starch, they are used to encapsulate drugs and nutritional ingredients, especially those sensitive to moisture and oxygen, protecting the ingredient stability.

Nedir Avantajları Pullulan Capsules over HPMC Capsules?

· Outwardly, pullulan capsules are exceptionally clear and glossy, staying more visually appealing compared to HPMC capsules.

· Because of the relatively simple production process, pullulan capsules have higher purity and a higher degree of naturalness.

· This type of capsules, highly resistant to cross-linking, can ensure more reliable dissolution and dissolve faster than HPMC capsules

3 Starch and PVA Capsules

Starch and PVA capsules have much shorter histories than those of gelatin and vegetarian capsules. Starch capsules are mainly made from starch, including that from corn, potatoes, tapioca and wheat. These starches are processed and refined to get highly purified starch for encapsulation.

PVA capsules are made from polyvinyl alcohol— a synthetic polymer material, possessing unique benefits such as good water solubility and film-forming properties.

These two capsule forms are widely used in pharmaceutical and health product industries to encapsulate medicines, vitamin, minerals and other active ingredients. Their shells are strong enough to contain kinds of formulation, especially suitable for containing products that require slow release in human bodies.

Types of Capsules according to Textures

Categorized according to functions, types of kapsüller include hard capsules and soft capsules.

1. Hard Capsules

Usually known as hard gelatin capsules, hard capsules are traditionally made from gelatin but can also be made from plant-based materials. Suitable for enclosing both medicines and vitamins, hard gel capsules generally encapsulate solid oral dosage forms or sometimes even liquid formulations, protecting medications encased in a gelatin shell.

2. Soft Capsules

Known as soft gel capsules, soft capsules are soft in the capsule shell and ideal for enclosing liquid dosage forms including fish oil or other supplements. With soft texture facilitating the ease of swallowing, the capsules are usually made from gelatin but can also be made from vegetarian alternatives like cellulose.

Not similar to hard capsules that have two parts (a body and a cap), a soft capsule is made from a single piece of gelatin or other material. Soft capsules are typically filled with liquid or semi-solid ingredients.

Types of Capsules according to Functions

Categorized according to functions, types of kapsüller can be shown in this table:

1. Enteric Capsules

Coated with a kind of pH-sensitive polymer, enteric capsules have special layers as their coatings resist dissolution in stomach acid, in order to reach the purpose that active ingredients enter small intestines, breaking down in the more alkaline environment of small intestines.

2. Sustained-release Capsules

Designed to release active ingredients slowly and continuously, sustained-release capsules can let the drug releasing extend over a period for about 10 hours or longer, leading to stable drug releasing levels and the consistency of drugs’ therapeutic concentration in the bloodstream.

3. Controlled-release Capsules

Controlled-release capsules target specific locations of intestinal tracts, providing more precise control on drug release compared to sustained-release one. Dahası ne var, controlled-release capsules can maintain therapeutic drug levels for 24 hours or above, thereby reducing medicine doses and simplifying medication regimens.

Types of Capsules according to Uses

Categorized according to the application, types of capsules are shown in this table:

1. Pharmaceutical Capsules

Drug kapsüller serve the purpose of encapsulating active pharmaceutical ingredients (API'si) in shells, typically made of gelatin or plant-based materials. They are used to shield medicines from the surrounding and ensure the delivery of medications for therapeutic uses, improving dosage accuracy and the effectiveness of curing diseases.

2. Dietary Supplement Capsules

When it comes to shapes of capsules, dietary supplement capsules are more good-looking. They are generally more consumer-oriented and visually attractive. Different from pharmaceutical capsules that contain API, Dietary supplement capsules may contain vitamins, herbal ingredients, and fatty acids like Omega 3, which support human health but not treat diseases.

Comparing Capsules of Different Outward Features

1. Kapsül boyutları

Selecting medications with the capsule size suitable for your dosage demand would be better to manage personal health.

Ranging from size 000 boyuta 5, capsule sizes differ with larger numbers indicating smaller volumes. Different formulations and specific dosage requirements influence the choice of capsule sizes. Bigger capsules (örneğin. 000, 00) are suitable for medicines or supplements with high dosages, while smaller capsules (örneğin. 4, 5) are ideal options for containing potent or pediatric formulations.

For more detailed information about capsule sizes, please view this chart:

2. Different Capsule Colors

Capsules are produced with many different colors.

Why do capsule colors differ?

Tüketiciler için, they can distinguish among various medications, lowering the risk of wrong medication taking. Ek olarak, different capsule colors will deliver helpful psychological effects on patients. Örneğin, blue or green is usually related with calming effects, while orange or red will be associated with aggressive efficacy.

For pharmaceutical enterprises, unique colors of capsules help promote the branding recognition and the image of products standing out of competitive goods on pharmacy shelves. Üstelik, nice colors make products more attractive to consumers.

Besides, some dark colors, such as brown or black, can protect light-sensitive capsule ingredients from impacts caused by UV exposure.

3. Capsule Transparency

Some capsules are visually transparent, allowing you to see the pharmaceutical ingredients inside. Transparent capsules are also typically made from gelatin or plant-based materials. The transparency is achieved by professionally processing highly purified substances into clear, see-through capsule shells.

Why are some capsules made transparent?

Being transparent can enhance the aesthetic exterior, helping capsules stay visually appealing, especially when the API is colorful or the transparent shell has an interesting texture. This appearance renders benefits to capsule marketing.

Bu sırada, transparent capsules also benefit improving consumer trust, as being able to see contents inside capsules allows consumers to visually be informed what they are consuming.

Çözüm

For workers and professionals in industries of pharmaceuticals and nutraceuticals, it’s essential to understand different Kapsül türleri to ensure the quality of work on tailored drug delivery, Hasta uyumluluğu, product stability and shelf life, capsule compatibility with formulations, vesaire.